R. Alta Charo
Warren P. Knowles Professor of Law and Bioethics
B.A., Biology, Harvard University, 1979
J.D., Columbia University School of Law, 1982
R. Alta Charo is the Warren P. Knowles Professor of Law and Bioethics at the University of Wisconsin at Madison. In the past, she also has served on the faculty of the UW Masters in Biotechnology Studies program and the Dept. of Medical History and Bioethics at the School of Medicine & Public Health.
For the 2019-2020 academic year, she is on leave while a Berggruen fellow at the Center for Advanced Study in Behavioral Sciences at Stanford University.
Alta Charo (B.A. biology, Harvard 1979; J.D. Columbia, 1982) is an elected member (2004) of the World Technology Network and (2005) the Wisconsin Academy of Sciences, Arts and Letters. And in 2006 she was elected to membership in the National Academies' Institute of Medicine (IOM) (now known as the National Academy of Medicine). In 2013 she was awarded the Adam Yarmolinsky Medal for her service to the IOM.
Professor Charo served on President Obama's transition team, where she was a member of the HHS review team, focusing her attention particularly on transition issues related to NIH, FDA, bioethics, stem cell policy, and women's reproductive health. She was on leave 2009-2011 to serve as a senior policy advisor on emerging technology issues in the Office of the Commissioner at the US Food & Drug Administration.
Professor Charo offers courses on public health law, bioethics, biotechnology law, food & drug law, reproductive rights, stem cell policy, torts, and legislative drafting. In addition, she has served on the UW Hospital clinical ethics committee, the University's Institutional Review Board for the protection of human subjects in medical research, and the University's Bioethics Advisory Committee. She has been a visiting lecturer at law and medical schools in Argentina, Australia, Canada, China, Cuba, France, Germany, and New Zealand. In 2006, she was a visiting professor of law at the University of California -- Berkeley, School of Law (Boalt Hall).
Prior to her arrival at UW in 1989, Professor Charo served as Associate Director of the Legislative Drafting Research Fund of Columbia University (1982-1985); Fulbright Junior Lecturer in American Law at the Sorbonne in Paris (1985-1986); legal analyst for the Biological Applications Program of the congressional Office of Technology Assessment (1986-88); and American Association for the Advancement of Science Diplomacy Fellow for the Policy Development Division of the Office of Population at the U.S. Agency for International Development.
Professor Charo has authored or contributed to over 100 articles, book chapters and government reports on law and policy related to environmental protection, reproductive health, new reproductive technologies, medical genetics, stem cell research, science funding, and research ethics. She has served as a member of the boards of the Alan Guttmacher Institute and the Foundation for Genetic Medicine, the National Medical Advisory Committee of the Planned Parenthood Federation of America, and the program board of amfAR, the Foundation for AIDS Research. She has also been on the boards of the Society for the Advancement of Women's Health and the former American Association of Bioethics, as well as the ethics advisory board of the Howard Hughes Medical Institute. In addition, she has served as a consultant to the National Academy of Science's Institute of Medicine and the former NIH Office of Protection from Research Risks.
Charo has also served on several expert advisory boards of organizations with an interest in stem cell research, including CuresNow, the Juvenile Diabetes Research Foundation, the International Society for Stem Cell Research and WiCell, as well as on the advisory board to the Wisconsin Stem Cell Research Program. From 2005-2009 she was a member of the ethics standards working group of the California Institute for Regenerative Medicine. Also in 2005, she helped to draft the National Academies' Guidelines for Embryonic Stem Cell Research, and in 2006 she was appointed to co-chair the National Academies' Human Embryonic Stem Cell Research Advisory Committee. Later she chaired a workshop on the growing problem of misleading advertising and patient endangerment by unscrupulous clinics purporting to offer stem cell therapy.
Charo's advisory committee service for the federal government includes the 1994 NIH Human Embryo Research Panel, and (1996-2001) President Clinton's National Bioethics Advisory Commission where she participated in drafting its reports on "Cloning Human Beings"(1997); "Research Involving Persons with Mental Disorders that May Affect Decisionmaking Capacity"(1998); "Research Involving Human Biological Materials: Ethical Issues and Policy Guidance"(1999); "Ethical Issues in Human Stem Cell Research"(1999); "Ethical and Policy Issues in International Research: Clinical Trials in Developing Countries" (2001); and "Ethical and Policy Issues in Research Involving Human Participants" (2001).
At the National Academies, Professor Charo is a member of the IOM Council, the Board on Health Sciences Policy, and the Committee on Science, Technology and Law. From 2001-2008 she was a member of the Board on Life Sciences. She served as its liaison to the Committee on Research Standards and Practices to Prevent Destructive Applications of Biotechnology and co-chaired its committee to develop national voluntary guidelines for stem cell research. She also served from 2006 to 2013 as a member of the Institute of Medicine's Board on Population Health and Public Health Practice as well as its Committee on Smallpox Vaccination Program Implementation and its committee to review the FDA and the U.S. national system for the assurance of drug safety.
Professor Charo also has completed service as a member of a working group of the NIH Council of Councils, reviewing the use of chimpanzees in NIH-funded research, an IOM committee reviewing the current pediatric vaccine schedule, an NAS committee updating the code of responsible conduct of science, an IOM committee on the use of mitochondrial replacement techniques, and on the advisory council for the NIH National Center for the Advancement of Translational Sciences.
From 2015 - 2017 she was a member of the National Academies' Human Gene Editing Initiative and co-chaired its committee charged with making recommendations on the use of gene-editing for both somatic and germline (heritable) changes in humans. She also was co-founder and then co-chair of the NAS/NAM Forum on Regenerative Medicine, served on the Program Board of the Greenwall Foundation and was a witness for the congressional panel looking at the practice of fetal tissue research. At present she is a member of the World Health Organization's expert advisory committee on global governance of genome editing.
Ms. Charo was born in Brooklyn, NY. She is fond of poker, foreign language study, cats, home renovation, Harry Potter books, old movies, roller coasters, salsa music, Jane Austen novels and Star Trek.
Selected publications are available at: http://ssrn.com/author=549738
Her email signature lines have included, from time to time, the following:
To the wrongs that need resistance, To the right that needs assistance, To the future in the distance, Give yourselves.
-- Carrie Chapman Catt (1859 " 1947)
Injustice anywhere is a threat to justice everywhere.
-- Martin Luther King Jr. (1929 - 1968)
Aim above morality. Be not simply good, be good for something.
--Henry David Thoreau (1817 - 1862)
Action indeed is the sole medium of expression for ethics.
-- Jane Addams (1860 - 1935)
Always do right -- this will gratify some and astonish the rest.
-- Mark Twain (1835 - 1910)
- Biotechnology policy
- Emerging technology policy
- Drug safety
- Medical Research
- Reproductive rights
Activities & Scholarship
Alta Charo presented "Rogues and Regulation," a talk on global governance options for advances in genetic medicine, for the Grand Rounds series at the University of California, San Francisco Medical School. She also presented the talk at Chan Zuckerberg BioHub.
Alta Charo's article, "A Professional Standard for Informed Consent for Stem Cell Therapies," was published in the Journal of the American Medical Association on November 5, 2019.
Alta Charo gave the plenary presentation at the annual meeting of the American Gynecological and Obstetrical Society in Chicago. Her talk focused on public control and governance of science.
In September, Alta Charo presented "Governance Options for the Life Sciences" before the National Academies' Committee on Developing a Research Agenda and Research Governance Approaches for Climate Intervention Strategies that Reflect Sunlight to Cool the Earth.
Alta Charo's article, "A Professional Standard for Informed Consent for Stem Cell Therapies" (co-authored with Jeremy Sugarman and Roger Barker), appears in the August 12 online edition of the Journal of the American Medical Association.
Alta Charo's article, "Human Organoids: A New Dimension in Cell Biology," appeared in Molecular Biology of the Cell in April. Human organoid cultures provide the potential to study disease processes with the same scrutiny and depth of analysis customary for research with nonhuman model organisms. This article includes guidelines for reproducibility, culturing, sharing of patient materials, patient consent, training and communication with the public.
Alta Charo spoke at a Nuclear Threat Initiative meeting that convened in London in April, as part of her work as a member of the "Biosecurity Innovation and Risk Reduction Initiative." Charo's presentation focused on the role funders and journals can play in reducing the risk that biotechnology research can result in biohazards or be turned into a bioterrorism tool.
Alta Charo participated in a March workshop on the problems created by the Supreme Court's use of unvetted, unchallenged scientific and other factual claims made in amicus briefs, and on possible responses by the legal and scientific communities. The workshop was sponsored by the Annenberg Public Policy Center and the Sunnylands Trust.
Alta Charo has been appointed to the newly formed World Health Organization expert advisory committee on "Developing Global Standards for Governance and Oversight of Human Genome Editing."
Alta Charo has been named to the Technical Advisory Group for the Health Security Interface at the World Health Organization. The group provides advice to WHO across areas related to the interface between the public health and national or international security.
Alta Charo's article (co-authored with Josh Sharfstein), "Medical Products in the 21st Century: Off-label Marketing and First Amendment Concerns," was published in the Journal of the American Medical Association in September.
Alta Charo was a keynote speaker at "Wait, What?" a conference organized by the Department of Defense Advanced Research Projects Agency. She spoke on how deeply held beliefs have threatened basic science research, and on the possibility of First Amendment protections for controversial research as a form of expressive conduct. Video of her presentation is available online.
Alta Charo delivered the annual Daniel W. Foster, M.D. Lecture in Medical Ethics at the University of Texas-Southwestern Medical Center in November 2009. She spoke on “The Celestial Fire of Conscience: Is There a ‘Right’ to Refuse Medical Services?”
News & Media
Wednesday, Jan 8, 2020Alta Charo discusses the gene drive dilemma: We can alter entire species, but should we?
The New York Times
Thursday, Jan 2, 2020Chinese scientist who claimed to create gene-edited babies sentenced to prison; Alta Charo responds
Wednesday, Dec 11, 2019Gene surgeons aim to repair fetal problems before they start; Alta Charo comments
The Mercury News
Monday, Nov 11, 2019Alta Charo appears in Human Nature, a documentary about CRISPR
Friday, Aug 2, 2019Alta Charo wins Center for Advanced Study in the Behavioral Sciences fellowship
Monday, Jun 10, 2019Trump administration curtails fetal tissue research; Alta Charo responds
Wednesday, May 8, 2019Chinese bioethicists call for regulation 'reboot' after country's gene-edited baby scandal; Alta Charo comments
Tuesday, Apr 23, 2019Alta Charo: 'Born alive' bills create the false impression that abortion providers practice infanticide
Milwaukee Journal Sentinel
Monday, Apr 15, 2019 Stanford professor faces investigation into involvement in gene-edited twins controversy; Alta Charo comments
The New York Times
Wednesday, Mar 27, 2019What is the world to do about gene editing? Alta Charo weighs in
New York Review of Books
Wednesday, Mar 13, 2019Alta Charo discusses call for 5-year global ban on human germline editing
Tuesday, Mar 5, 2019Alta Charo discusses China's plan to step up oversight of high-risk clinical trials
Tuesday, Feb 26, 2019How will the CRISPR baby scandal affect the future of human gene editing? Alta Charo discusses
Tuesday, Feb 12, 2019Alta Charo discusses new 'Fountain of Youth' pill: can it be proven safe and effective?
Kaiser Health News